Effects of endogenous ammonia on neutralization of inhaled sulfuric acid aerosols by Susan M. Loscutoff Download PDF EPUB FB2
Exhaled concentration of ammonia, sulfuric acid and ammonium bisulfate were measured to determine the neutralization of inhaled aerosol by ammonia in the lung. Unneutralized sulfuric acid aerosol was detected in exhaled air only during exposure to mg/cu.m H2SO4 with approximately 25 percent of the total exhaled sulfate measured as H2SO4.
Larson et al., () reported neutralization of mg/m3 inhaled sulfuric acid aerosols in humans, with an average ammonium to sulfate molar ratio in exhaled air greater than or equal to one. Neutralization of inhaled sulfuric acid aerosols may be important in terms of acute and chronic toxicity.
Effects of endogenous ammonia on neutralization of inhaled sulfuric acid aerosols Author: Susan M Loscutoff ; Health Effects Research Laboratory (Cincinnati, Ohio) ; Pacific Northwest Laboratory.
Depression of Ammonia Uptake to Sulfuric Acid Aerosols by Competing Uptake of Ambient Organic Gases. Environmental Science & Technology45 (7), DOI: / by: Effects of endogenous ammonia on neutralization of inhaled sulfuric acid aerosols / by Susan M.
Loscutoff. By Susan M. Loscutoff. Abstract. x, 38 : Susan M. Loscutoff. Effects of Inhaled Acid Aerosols on Respiratory Function: The Role of Endogenous Ammonia. Journal of Aerosol Medicine2 (2), DOI: /jamCited by: Effects of respirable aerosols of sulfuric acid, ammonium sulfate, sodium sulfite, and ammonium persulfate on lungs of rats are reviewed.
An experimental study of the reaction rate between monodisperse sulfuric acid aerosols and ammonia gas is described. Reactions took place in a laminar flow reactor at 24 °C and 6% relative humidity, and reaction products were sampled from the core of the flow so that reaction times were well by: Abstract.
This paper reviews the emerging issue of acid aerosols, primarily from an American perspective. Emission sources, ambient levels, measurement methods, and health effects are discussed, as well as the background of the issue in the United States.
The balanced equation for the reaction of ammonia with sulfuric acid is 2NH3 + H2SO4 > (NH4)2SO4 OR 2NH4OH + H2SO4=(NH4)2SO4+2H2O. SCHLESINGER, R.B., ANDGRAHAM, J.
Fundum. Appl. Toxicol. 18, A symposium entitled, Health Effects of Atmospheric Acid Aerosols: A Model Problem in Inhalation Toxicology and Air Pollution Risk Assessment, was held at the 30th Annual Meeting of the Society of Cited by: To determine if respiratory ammonia (NH3) alters airway responses to sulfuric acid (H2SO4) aerosols, 15 asthmatics inhaled a H2SO4 aerosol at high and low respiratory NH3 : Morton Lippmann.
When the responses of humans and rabbits were compared, it was apparent that to produce a comparable change in clearance rate, rabbits required approximately a MEASUREMENT OF RESPIRATORY TRACT AMMONIA twofold higher acid exposure concentration than did humans (Schlesinger et al., ).Cited by: 8.
Effects of inhaled acid aerosols on lung mechanics: an analysis of human exposure studies. Endogenous oral ammonia inhibits sulfuric acid aerosol induced bronchoconstriction in exercising asthmatics (abstract).
Measurements of respiratory ammonia and the chemical neutralization ofinhaled sulfuric acid aerosol inanesthetized : M J Utell. The rate of neutralization of sulfuric acid aerosol by ammonia gas has been measured in a laboratory flow reactor for particle diameters between and μm and for relative humidities between 8 and 80%.Cited by: The extent of neutralization of inhaled H2SO4 aerosol by endogenous NH3 has been measured In the surgically isolated upper airways of anesthetized dogs.
Neutralization Cited by: sulfuric acids. Neutralization, by ammonia, leads to the production of bisulfates and sulfates. Sulfur dioxide is a colourless gas that is readily soluble in water. Sulfuric acid is a strong acid that is formed from the reaction of sulfur trioxide gas (SO3) with water.
Sulfuric acid is strongly Size: KB. Abstract. Polluted air at times contains a number of acidic compounds, most notably particulate acid in the form of partially neutralized sulfuric acid (H 2 SO 4) and acidic vapor in the form of nitric acid (HNO 3).This chapter discusses model estimates of the respiratory fate of acidic particles and gases with emphasis on the neutralization that occurs in the airways due to respiratory Cited by: 6.
• Feed: Ammonia (NH 3) and sulfuric acid (H 2 SO 4). Surplus ammonia is a by-product from the onsite urea production plant. An option exists to use sulfuric acid produced by several nearby refineries. • Technologies: Veolia’s HPD® PICTM (draft tube baffle) crystallizer, 2-stage pusher centrifuges, drying, screening, packaging, and File Size: KB.
In the studies of Spektor et al. and Leikauf et al. (, ), the effects of sulfuric acid aerosols with small droplet sizes ( µm) on the mucociliary clearance in volunteers were studied.
To prevent neutralization of the acid in the mouth by endogenously formed ammonia, the volunteers were exposed only via the nose. Effects of sulfuric acid aerosol inhalations Effects of sulfuric acid aerosol inhalations Lippmann, Morton; Schlesinger, Richard B.; Leikauf, George Submicrometer H2S04 droplets can affect pulmonary functions in humans.
The lowest concentration which has been reported to produce a statistically significant effect on pulmonary mechanics is 1 mg/m3. Endogenous removal of ammonia: The main route for removal of ammonia carried to the liver by the portal vein is incorporation into urea by enzymes of the urea cycle in the periportal Size: 84KB.
A Novel System for the in Vitro Exposure of Pulmonary Cells to Acid Sulfate Aerosols chief among which are neutralization of inhaled acids by endogenous ammonia and variations in deposition with inhaled particle size.
The system consists of two subunits, a generation/delivery component and a cell exposure component. Sulfuric acid Cited by: The extent of neutralization has important implications for aerosol mass, hygroscopicity, and acidity.
When ammonia is in excess, standard thermodynamic models predict that sulfuric acid should be fully neutralized with an ammo nium -sulfate aerosol neutralization ratio f =. The potential for ammonia produced naturally in the mouth to modify the effects of inhaled sulfuric acid aerosol particles was investigated in healthy adults.
If significant chemical neutrali- zation were to occur before deposition the irritant potency of the aerosol might be significantly reduced. Sulfuric acid 55 works Search for Search. Use of sulfuric-nitric acid for the recovery of plutonium from HEPA fi D.
Clark Not In Library. Miniature acid-condensation system Not In Library. Effects of endogenous ammonia on neutralization of inhaled sulfuric ac Susan M.
Loscutoff Not In Library. Not In Library. Relative humidity effects on gas-to-particle conversion processes were analyzed by particulate NH 4 concentration originally formed from the neutralization processes with the secondary pollutants in the atmosphere. INTRODUCTION Atmospheric acid gases (sulfuric acid [H 2 SO 4], nitric acid [HNO 3], and hydrochloric acid [HCl]) have not only beenCited by: Effects of endogenous ammonia on neutralization of inhaled sulfuric ac Susan M.
Loscutoff Read. Read. Froisland Read. Sulphur, sulphur dioxide, and sulphuric acid Read. Corrosion in sulfuric acid CORROSION/85 Symposium on Corr Read. Sulfuric acid manufacture and effluent control, Accessible book, sulphuric acid, acid.
What are the side effects of inhaling ammonia. Exposure to high concentrations of ammonia in air causes immediate burning of the nose, throat and respiratory tract. This can cause bronchiolar and alveolar edema, and airway destruction resulting in respiratory distress or failure/5(3).
Uses and hazards of sulfuric acid. The majority of sulfuric acid that is produced is used to make is often by reacting the sulfuric acid with ammonia, or ammonium hydroxide. Examples of acids are hydrochloric acid, sulfuric acid, hydrobromic acid and perchloric acid.
If you're trying to neutralize an acidic solution, any base will neutralize it. Ammonia, Sodium.Isopropyl alcohol and isopropyl alcohol manufacture (strong-acid process) were considered by previous IARC Working Groups in and (IARC,).
Since that time, new data have become available, which have been incorporated in this Monograph, and taken into consideration in the present evaluation.
A separate Monograph on ‘Mists from Strong Inorganic Acids’ – updating earlier.Confounding features and biases were minimal. Exposure to ammonia, for a few minutes to several hours, was associated with neurobehavioral impairment measured after 22 months.
Thus inhaled ammonia shares the toxicity of endogenous ammonia. Effects were persistent and are probably permanent. Introduction.